abstract |
Porous orodispersible tablet with microscopic pores, comprising a therapeutically effective amount of glycopyrrolate, the porous orodispersible tablet with microscopic pores disintegrating in the mouth in less than 60 seconds, the porous orodispersible tablet with microscopic pores by freeze-drying a liquid formulation having a pH in the range of 4.0 to 6.5, preferably in the range from 4.0 to 5.0, is produced, the liquid formulation comprising at least one filler, at least one binder, at least one emulsifier, at least one disintegrant and water; andwherein the porous orodispersible tablet with microscopic pores preferably has an increased bioavailability compared to a reference tablet which comprises the same amount of glycopyrrolate. |