http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-2015850-A1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J19-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J19-00 |
filingDate | 1970-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1971-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | DE-2015850-A1 |
titleOfInvention | Inotropic cardenolide genies |
abstract | Cardeolide-genines (I) have a pos. inotropic action on the heart and are intermediates for cardioactive agents. In (I) X=F, Cl, CH3 or lower alkoxy; R2=H, acyl or other easily hydrolysable OH-protective group; R2=OH or OH protected by acyl or other hydrolysable group; R3, R4 (if same)-H, OH or OH protected by acyl or other hydrolysable group; or R4=OH or OH protected by acyl or other hydrolysable group; R2, R3 jointly with 0 in 5-posn gives an orthoester residue. Steroid esters (II) structure (I) with the pyran ring deriv substituent replaced by -CO-CH2-O-CO-CH(X)- -OR5 where substituents have similar meaning to those in (I) but R1 and R4 are not H, are used to prepare (I) by the intramolecular cyclisation of (II). |
priorityDate | 1970-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 69.