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filingDate 1970-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1970-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber DE-2009115-A1
titleOfInvention Patentwesen Ost-Berlin WP138379 Process for the production of a macrolide antibiotic
abstract A macrolide antibiotic is prepd. by aerobic incubation of Streptomyces hygroscopicus J A6599 on a suitable mutant, for 2-5 days at 28-32 degrees. The mycelim is sepd., extracted with halohydrocarbon, ketone, orester (pref. BuOAc), the soln. back-extracted with acid or acid buffer, the aqueous extract back-extd. with halohydro-carbon or ester (pref. CHCl3) the concentrated product pptd. with pet spirit and opt. purified by chromatography.
priorityDate 1969-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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