| abstract |
The present invention relates to 6-position substituted indolinones of the general formula DOLLAR F1 in the DOLLAR AR¶1¶ to R¶5¶ and X as defined in claim 1, their isomers and their salts, in particular their physiologically tolerable salts, which are valuable Pharmacological properties, in particular an inhibitory effect on various receptor tyrosine kinases and cyclin-CDK complexes and on the proliferation of endothelial cells and various tumor cells, medicaments containing these compounds, their use and processes for their preparation. |