http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-19941657-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3ddd5f458039b813e6ccbbaa3fc15666 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-185 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D227-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-092 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-185 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D227-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-62 |
filingDate | 1999-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e5e7bd98bad891243ea0a268d430800 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4cdd0e2f69cecce32514746766f1b28f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff4c8f885d4f4565773d92300523e738 |
publicationDate | 2001-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | DE-19941657-A1 |
titleOfInvention | Cinnamic acid nitriles, process for their preparation and use |
abstract | The invention relates to substituted cinnamic acid nitriles of the formula I DOLLAR F1 with DOLLAR AX = CN, COOR 4, CONR 5 R 6, COAryl or COalkyl, DOLLAR AR 1 = H, alkyl, arylalkyl, 4- (2-alkoxyphenyl) -1-piperazinylFalkyl, DOLLAR AR 2 and R 3 = independently of one another H, hydroxy, alkoxy, DOLLAR AR 4 = H, alkyl, 4- (2-alkoxyphenyl) -1-piperazinylFalkyl, DOLLAR AR 5 = H, alkyl, alkoxyalkyl, aryl, arylalkyl, 4 - (2-Alkoxyphenyl) -1-piperazinylFalkyl, DOLLAR AR 6 = H, alkyl, DOLLAR A or NR 5 R 6 together = cyclic amine such as pyrrolidine, morpholine, piperidine, subst. Piperazine, where at least one of the radicals R 1, R 4 or R 5 is a 4- (2-alkoxyphenyl) -1-piperazinylF-alkyl radical, DOLLAR A and their addition salts with pharmacologically acceptable acids. DOLLAR A The compounds are effective as medicines for the prophylaxis and treatment of benign prostatic hyperplasia. Methods for making the cinnamic acid nitriles are also suggested; an appropriately substituted benzaldehyde is subjected to a Knoevenagel condensation with an appropriately substituted acetonitrile. |
priorityDate | 1999-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
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