http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-19922052-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6d42a0a7c18ef9237d30c18fc9a295b3 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6809 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6886 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6809 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 1999-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_16b0b54b2c070549fe6b87ae8c5080cf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f257f490ff3f70921004b5a643d05b0a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc8d22714e56fa06148cd9bc7ea8f1bb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f17c236b612f9fe9be159cb67afc7999 |
| publicationDate | 2000-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DE-19922052-A1 |
| titleOfInvention | Methods for demonstrating the effect of different chemotherapeutic agents and / or radiation therapy for malignant diseases, and methods for selecting effective therapeutic agents for their therapy |
| abstract | The invention relates to a method for detecting the effect of different chemotherapeutic agents and / or radiation therapy in malignant diseases, the expression profiles of tumor and / or cell growth and / or apoptosis-associated genes and / or the individual differences (mutations) in the Gene sequences can be determined. Changes in connection with chemotherapeutic agents and / or radiation therapy are identified, represented and diagnosed. Furthermore, the invention relates to a method for selecting effective therapeutic agents for the treatment of malignant diseases. The status of cell cycle genes and / or of apoptosis-associated target genes or of their gene products in body fluids, cells and / or organs is determined and their effects on corresponding therapeutic agents are evaluated diagnostically. In a preferred embodiment, Bax and p53 expression or mutations are examined, and information derived therefrom for individual-specific therapy decisions in leukemia and other malignant diseases is provided. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011068863-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8624027-B2 |
| priorityDate | 1999-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 54.