| abstract |
New tetrahydrofuran derivatives of the general formula I DOLLAR F1 in which B, E, R · 1 ·, R · 2 ·, R · 3 ·, R · 4 ·, n, m, o and p have the meanings given in patent claim 1 and their meanings Physiologically acceptable salts or solvates are integrin inhibitors and can be used to combat thrombosis, heating, coronary heart disease, arteriosclerosis, inflammation, tumors, osteoporosis, infections and restenosis after agioplasty or in pathological processes that are maintained or propagated by angiogenesis. |