| abstract |
The invention relates to a complex of non-occurring, specifically complex-forming proteins comprising the following components: a) at least one ligand specific for a target structure, b) at least one protein containing a mutant dimerization domain, wherein the mutated dimerization domain is by mutation of a naturally occurring one Dimerization domain, said mutant dimerization domain can specifically interact with component c), and component b) is covalently linked to component a), c) at least one protein containing a mutant dimerization domain, said mutant dimerization domain being by mutation of a naturally occurring one Dimerisierungsdomäne has been derived, this mutated Dimerisierungsdomäne can interact specifically with component b) and the component c) is covalently connected to the component d), and d) at least one effector. Furthermore, the invention relates to the use and preparation of these complexes and nucleic acid constructs encoding said proteins and their use. |