abstract |
The present invention relates to a method for producing a whole blood-compatible adsorber material which is suitable for removing lipoproteins, in particular LDL cholesterols, in the extracorporeal circuit. More specifically, the invention relates to a process for the production of such adsorber materials, in which at least one polyelectrolyte by direct, covalent binding to a polymer matrix as a solid phase, which contains a strained heterocyclic system as a functional group, with ring opening, in particular nucleophilic ring opening, of the strained heterocyclic system, for example under Formation of a beta-hydroxy group is bound. |