| abstract |
The present invention relates to substituted indolinones of the general formula DOLLAR F1 in the DOLLAR AR¶1¶ to R¶5¶ and X are as defined in claim 1, their isomers and their salts, in particular their physiologically acceptable salts, which have valuable pharmacological properties, in particular an inhibiting effect on various kinases and cyclin / CDK complexes and on the proliferation of various tumor cells, medicaments containing these compounds, their use and processes for their preparation. |