| abstract |
Indole derivatives of formula R<1>-(CH2)n-(Y)q-(Z)r-CO-NH-R<2> (I) and their salts are new. R<1> = 3-indolyl optionally mono- or disubstituted by A, OA, OH, Hal, CN, NO2, NH2, NHA, NA2, COA, CONH2, CONHA, CONA2, CH2OH, CH2OA, CH2NH2, CH2NHA, CH2NA2, COOH and/or COOA; R2 = a group of formula (a)-(d): m = 1 or 2; n = 0-4; Y = 1,4-cyclohexylene, 1,3-pyrrolidinylene, 1,4-piperazinylene or 1,4-piperidinylene, optionally partially dehydrogenated; Z = (CH2)n or (CH2)nNH; q = 0 or 1; r = 0 or 1; R<3> = A; R<4> = OA; Hal = F, Cl, Br or I; A = 1-6C alkyl; provided that r and q are not both 0. |