abstract |
methodnfor the preparation of (S) -N, N'-bis [2-hydroxy-1- (hydroxymethyl) ethyl] -5- (2-acetoxypropionylamino) -2,4,6-triiodoisophthalamidenby reacting L-S- (2-acetoxypropionylamino) -2,4,6-triiodoisophthalic acid dichloridenwith 2-amino-1,3-propanediol in a solvent in the presencena base, characterized in that the solvent N-methylpyrrolidonenis. |