| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e153dc6a94c515910fd73e21e15c232 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-62 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-575
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 |
| filingDate |
1996-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_166929ac28b2268d73ba96008efd6140
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1c4e85723ff1b8a6010ef586cf6e2cb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0be2e63b96197dd27c58e41115ab8ac2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5caa405bd1f75a802f9cca22132406c |
| publicationDate |
1996-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
DE-19605657-A1 |
| titleOfInvention |
Proinsulin derivative and process for the production of human insulin |
| abstract |
There is described a human proinsulin derivative of the formula: human insulin B chain - Z - human insulin A chain wherein Z is a polypeptide linker of the formula: U-U-X-P-J-(X')n-U-U in which: U is arginyl or lysyl; X and X' are amino acid radicals; P is prolyl; J is glycyl, arginyl or lysyl; n is 0 or an integer of from 1 to 5. There is also described a DNA sequence encoding the proinsulin derivative, which may be inserted into an expression vector. The vector is used to transform a microorganism, preferably Escherichia coli . Human insulin is prepared from the proinsulin derivative by enzymatic hydrolysis. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012115641-A1 |
| priorityDate |
1995-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |