| abstract |
Thiopyrimidine nucleosides. Title Cpds. of formula (I): (where Xis O or NH; R s 2-4C alkyl, 1-4C alkoxy, halogen, 2-5C alkoxycarbonyl, 3-6C alkoxycarbonyl-methyl or opt. alkylated or acylated amino or amino-methyl and Z is a protected sugar residue the linkage of which with the pyrimidine ring is beta-oriented) having antibacterial, antiviral, cytotoxic and enzyme-inhibiting activity are claimed. Processes for preparing these cpds. are described. |