http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-19545465-A1

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c7ad58d3c0b071069a8ee0cb8c8ba2e8
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-70
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-70
filingDate 1995-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7eb1689297dab269368f747ce93b5526
publicationDate 1997-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber DE-19545465-A1
titleOfInvention Process for the preparation of benzothiophene derivatives
abstract The invention relates to a new process for the preparation of benzothiophene derivatives of the formula (I), in which R<1>, R<2>, X, m and n have the meanings given in the description. In said process the preparation of the derivatives is such that (a) firstly compounds of the formula (II) HX-R<2> are reacted with chloroacetyl chloride; (b) the resulting chloroacetic acid derivatives of the formula (IV) are subsequently reacted with thioacetic acid in the presence of a base; (c) the resulting acetylthio-aceto derivatives of the formula (VI) are thereafter reacted with ammonia in methanol, optionally acidified and reacted with benzaldehyde derivatives of the formula (VIII) in the presence of a base and optionally; (d) the resulting benzothiophene-2-carboxylic acid derivatives of the formula (IX) are finally reacted with oxidising agents.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0220452-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0220452-A2
priorityDate 1995-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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