http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-1953954-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c9b262c842f9c7f3c38a61e1f2d892f1 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-28 |
| filingDate | 1969-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_862f4d7b5a6c500faa1296947e5317f3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_197f25007e11002ebc60bc6166be5623 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8431f737538d0eef7b6bfc01624ae18b |
| publicationDate | 1970-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DE-1953954-A1 |
| titleOfInvention | New substituted 4-thiazole alazomethines |
| abstract | Substd. 4-Thiazolylazomethines with anthelmintic activity New cmpds (I) (where X = H, 1-8C alkyl or isoalkyl, (CH2)n OR where n = 2-8 and R = 1-8C n- or iso-alkyl, mono- or poly-hydroxyalkyl, benzyl or a pyridine residue of formula: or an aromatic residue of formula: R1-R4=H or 1-5C alkyl; n = 0-2; R5-R9 = H, hal (pref. Cl), NO2, OH, Y, OY or COY; Y = 1-6C alkyl) are prepared by condensation of thiazole-4-aldehyde with an amine XNH2. The compds. are active against Ascaris lumbricoides suis and Eisenia sp. Their activity spectrum is broader than that of known anthelmintics, e.g. the EC50 = 1-2.5 mg/ml compared with 6.0 mg/ml for piperazine adipate. Oral toxicity in mice is low viz. 600-1300 mg/kg. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2230776-A |
| priorityDate | 1968-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 92.