| abstract |
Use of a guanidine derivative represented by the formulas (1), (2) or (3) or an acid addition salt thereof as a skin cosmetic for softening the keratin layer wherein in formula (1): A and B may be the same or different and each represents an alkylene group having 2 to 8 carbon atoms; D represents a single bond, -CO- or an alkylene group having 1 to 6 carbon atoms and which may have a substituent group; E represents a hydrogen atom, a lower alkyl group, an aralkyl group or an aryl group which may have a substituent group; m is an integer from 1 to 6; n is an integer from 1 to 6; and R 1 represents a hydrogen atom, a lower alkyl group or - (AO) m - (BO) n -DE, with the proviso that - (AO) m - (BO) n -DE is not a hydroxyethyl group when R 1 is a methyl group ; in formula (2): 1 is an integer of 1 to 10; G is a sulfonic acid group, carboxyl group or a phosphoric acid group; and R 1 is as defined above; ... |