http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-1801331-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_04c2e8a5790992b1fe88770ed838608e |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F15-025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-295 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F15-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-295 |
filingDate | 1968-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_21c3908061543c26b1245bb3f2b7ea8a |
publicationDate | 1970-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | DE-1801331-A1 |
titleOfInvention | Wisen serine complex and process for its preparation |
abstract | Fe (III) COMPLEXES WITH D-, L- AND/OR DL-SERINE ARE IRON SOURCES WITH IMPROVED RESORPTION. G3A. And contain Fe and serine in ratio 1 g. atom Fe : 1 mol. serine. Prepared by mixing an aqs. serine salt soln. (pref. serine Na salt soln.) with aqs. FeCl3 soln. in 1:1 molar ratio, filtering the resulting brown soln., then dialysing until the content of Cl- ions corresponds to the content of complexed Fe atoms (Cl:Fe = 1:1), and subsequently lyophilising the soln. (complexes can also be ppted. by adding large amounts of e.g. EtOH, MeOH or Me2CO). Pharmaceutical preparations for oral administration contain the above complexes, which have iron resorption in the GI tract of ca. 70% or more. Additional advantages are the complexes' stability over a pH range of 2-8 (ensuring unchanged passage through the GI tract after oral administration) and, because Fe is in the ferric state, almost unlimited storage stability and low toxicity compared with ferrous-amino acid preparations. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4067994-A |
priorityDate | 1968-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.