http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-17825464-T1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ff57144603c661f4b368824eae0729f |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-582 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y114-19001 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-815 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0071 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0008 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-04 |
| filingDate | 2017-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e08cb9533b97346bdd073c3c8005bfcc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bad5b9b3235694ab081e432d3dfe1a23 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_014963dc7ccb9ba28a7f81029c7d86a5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b98a3d65cb2feff24926869dad8344a |
| publicationDate | 2019-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DE-17825464-T1 |
| titleOfInvention | METHOD FOR PRODUCING FATTY ALCOHOLS AND DERIVATIVES THEREOF IN YEAST |
| abstract | Oil-containing yeast cell capable of producing an unsaturated fatty alcohol, where the cell: i) expressing at least one heterologous desaturase capable of introducing at least one double bond into a fatty acid acyl-CoA; and ii) expressing at least one heterologous fatty acid acyl-CoA reductase capable of converting at least a portion of the unsaturated fatty acid acyl-CoA to an unsaturated fatty alcohol; and iii) a mutation which leads to a reduced activity of Fao1 (SEQ ID NO: 22) and a mutation which leads to a reduced activity of at least one of Hfd1 (SEQ ID NO: 4), Hfd4 (SEQ ID NO: 6), Pex10 (SEQ ID NO: 8) and GPAT (SEQ ID NO: 10), or a mutation which leads to a reduced activity of at least one protein which has at least 90% homology with Fao1 (SEQ ID NO : 22), and has a mutation that results in reduced activity of at least one of Hfd1 (SEQ ID NO: 4), Hfd4 (SEQ ID NO: 6), Pex10 (SEQ ID NO: 8) and GPAT (SEQ ID NO: 10), such as at least 91% homology, such as at least 92% homology, such as at least 93% homology, such as at least 94% homology, such as at least 95% homology , such as at least 96% homology, such as at least 97% homology, such as at least 98% homology, such as e at least 99% homology with Fao1 (SEQ ID NO: 22) and at least one of Hfd1 (SEQ ID NO: 4), Hfd4 (SEQ ID NO: 6), Pex10 (SEQ ID NO: 8) and GPAT (SEQ ID NO: 10), wherein the cell is capable of producing unsaturated fatty alcohols with a titer of at least 5 mg / l, such as at least 10 mg / l, such as at least 25 mg / l, such as at least 50 mg / l, such as at least 100 mg / l, such as at least 250 mg / l, such as at least 500 mg / l, such as at least 1 g / l, such as at least 2 g / l, such as at least 3 g / l, such as at least 4 g / l, such as at least 5 g / l, such as at least 6 g / l, such as at least 7 g / l, such as at least 8 g / l, such as at least 9 g / l l, such as at least 10 g / l. |
| priorityDate | 2016-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 69.