| abstract |
In one aspect, the present invention provides a chromatographic stationary phase material for various chromatographic methods represented by Formula 1: [X] (W) a (Q) b (T) c (Formula 1). X may be a high purity chromatographic core composition comprising silica core material, metal oxide core material, an inorganic-organic hybrid material, or a group of block copolymers thereof. W may be absent and / or may comprise a hydrogen and / or may comprise hydroxyl on the surface of X. Q can be a functional group that minimizes the retention variation over time (drift) under chromatographic conditions using low water concentrations. T may comprise one or more hydrophilic, polar, ionizable and / or charged functional groups that chromatographically interact with the analyte. In addition, b and c may be positive numbers, where the ratio is 0.05 ≤ (b / c) ≤ 100 and a ≥ 0. |