http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-112005003498-T5
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e562831ac734fa7ef92348ef1fdee789 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_373711468f5420207f0bc6e771b8538e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-94 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-94 |
| filingDate | 2005-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_931da61416c4520ce90912d984424768 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da34265952643767c2fc57f34307d2af |
| publicationDate | 2008-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DE-112005003498-T5 |
| titleOfInvention | Process for the preparation of quinazoline derivatives and preparation for the preparation of tumor diseases |
| abstract | A process for producing a compound (I) and its salt, characterized in that the compound (I), a quinazoline derivative, is represented by the following chemical formula is shown in the: X is -H, methyl or C 1-4 -alkyl; Y is substituted phenyl where n is 1, 2, 3 or 4 and R 5 may denote identical or different radicals selected from -H, methyl, trifluoromethyl, nitro, cyano, C 2-4 -alkyl, C 2-4 -alkoxyl, N- (C 2-4 ) -alkylamine, enzyme, hydroxyl, N, N-3N (C 1-4 ) -alkylamine, C 1-4 -alkylthio and C 1-4 -alkylsulfonyl; Z Is -O, -S or -NH; R 1 is methyl or C 1-4 alkyl; R 2 is C 1-5 -alkyl-R 6 , C 2-6 -alkenyl-R 6 or C 2-6 -alkynyl-R 6 , where R 6 is unsubstituted or substituted 4-piperidyl, optionally with one or more substituents Alkynyl, enzyme or amido on alkyl, alkenyl, alkynyl or 4-piperidyl; R 3 and R 4 are -H, methyl, C 1-4 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, cycloalkyl or heterocycloalkyl; Compound (I) can be synthesized by a reaction between compound (III) and compound (IV): in which: X-H, methyl or ... |
| priorityDate | 2005-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 64.