| abstract |
An oral or rectal pharmaceutical composition comprising a pharmaceutically acceptable carrier, and core-shell particles, wherein the core-shell particles have a core component and a shell component, and the core component comprises a potassium-binding cation exchange polymer, and the shell component is a crosslinked one synthetic polymer, wherein the synthetic polymer is formed by free radical polymerization of ethylene monomers selected from the group consisting of acrylic and methacrylic, styrene, diene, vinyl monomers and combinations thereof, and during the residence time in the and the passage through the gastrointestinal tract of an animal is not significantly decomposed. |