| abstract |
A device for preserving and administering an unoccluded topical oxybutynin composition, comprising: a) an unoccluded, topical oxybutynin composition comprising: I) a therapeutically effective amount of oxybutynin, II) a thickening agent, and III) 50 percent or more by weight of the non-occluded topical oxybutynin composition, a solvent . b) a reservoir for the non-occluded topical oxybutynin composition and c) a layered composite surrounding the reservoir and the unoccluded topical oxybutynin composition and comprising: i) a first polymer in contact with the unoccluded topical oxybutynin composition, and (II) a metal foil, which is bonded to the first polymer layer, which device can withstand a pressure of 30 pounds without bursting when compressed between two plates of a motorized dynamometer, and where the device is at 25 degrees Celsius and 60 percent relative humidity for twenty-six weeks Humidity was stored, the non-occluded, topical oxybutynin composition no longer ... |