abstract |
A process for the preparation of storage-stable, water / oil / water (W / O / W) multiple emulsions containing one or more active agents is described. The method comprises the steps a) stirring the active ingredient into an aqueous phase, b) emulsifying the aqueous phase by introducing the aqueous phase through a coarsely porous, porous membrane into an oil phase, c) phase inversion of the emulsion of b), by cooling the mixture at a cooling rate of at least 0.3 K / min, wherein either the aqueous phase in a) or the oil phase in b) or both phases, an emulsifier is added. |