http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-10315031-B4
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c02456d7156257e2f9ddd52c97e2abd5 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y10-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate | 2003-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2014-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5cd8b494f681f37067c115ca608a814 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2648a29136e933c5a2c533632e128120 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dced290e7b221a88739e9708da82e245 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e8c1c35c540fa456ff194fe7754d5d5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b16e3d2b0c009cc59d4f1d801e7eb087 |
publicationDate | 2014-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | DE-10315031-B4 |
titleOfInvention | Method for detecting sepsis and / or sepsis-like conditions |
abstract | Method for in vitro detection of sepsis, characterized in that it includes the following steps: a) isolating a plurality of sample RNAs from a human blood sample; a1) adding cDNA which is a sepsis specific gene or gene fragment b) labeling the sample RNA and / or the cDNA with a detectable marker; c) contacting the sample RNA with the cDNA under hybridization conditions; d) contacting control RNA, which is a control without SIRS / sepsis, with at least one cDNA under hybridization conditions; e) quantitatively detecting the labeling signals of the hybridized sample RNA and the control RNA; f) comparing the quantitative data of the marker signals to determine whether sepsis-specific genes or gene fragments are more or less expressed in the sample than in the control; g) wherein sepsis is present if the entirety of the following group of genes or gene fragments having the SEQ ID NO: 325, 268, 294, 235, 262, 240, 248, 331, 486, 251, 903, 196, 324, 672, 134, 363, 259, 168, 326, 671, 114, 253, 116, 489, 485, 273, 154, 187, 358, 495, 330, 327, 1511, 314, 339, 219, 328, 348, 272, 232, 349, 310, 65, 265, 361, 269, 652, 1755, 151, 275, 66, 317, 329 is overexpressed; and or the entirety of the following group of genes or gene fragments having the following SEQ ID NOs: 2050, 375, 211, 250, 1477, 130, 23, 46, 26, 764, 383, 298, 28, 146, 1352, 42, 257, 1502 , 203, 19, 12, 95, 188, 47, 45, 237, 706, 129, 1353, 137, 51, 43, 169, 1462, 59, 378, 246, 201, 67, 1597, 216, 490, 5 , 93, 142, 189, 1442, 152, 53, 238, 180, 491, 190, 148, 386, 245 are underexpressed. |
priorityDate | 2003-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 342.