abstract |
The invention encompasses the production and use of new 14β-alkyl-18-nor-steroids which can be prepared by reacting 17β-hydroxy-14α, 15α-epoxi-steroids using anhydrous acids or Lewis acids and subsequent derivatization. The resulting compounds can be used as intermediates for or as medicinal products in the human and veterinary field, the focus being on inflammatory processes, hormone replacement therapy and the use as enzyme inhibitors in the treatment of tumors. |