| abstract |
The invention relates to a multilayer drug form, composed of a) a neutral core, b) an inner coating of a methacrylate copolymer, c) an outer coating of a copolymer, which consists of 40 to 95 wt .-% radically polymerized C 1 - to C 4 -alkyl esters of acrylic or methacrylic acid and 5 to 60 wt .-% of (meth) acrylate monomers having an anionic group in the alkyl radical, characterized in that the inner coating consists essentially of a methacrylate copolymer, the at least 90 wt .-% of (meth) acrylate monomers having neutral radicals, a minimum film-forming temperature according to DIN 53787 of at most 30 ° C and contains the active pharmaceutical ingredient in bound form. |