abstract |
The invention relates to substituted isoxazole derivatives of the formula I. wherein the radicals R 1 , R 2 and R 3 have the meaning given in the description. The compounds according to the invention have an immunomodulating and / or cytokine release-inhibiting action and are therefore suitable for the treatment of diseases which are related to a disturbance of the immune system, in particular immunologically mediated inflammatory diseases. |