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filingDate 2002-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7fc9730ac9ed4125366d899e9d6cc550
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_540f40ad4e904eda8ad7d6bcb7e2e878
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publicationDate 2004-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber DE-10234524-A1
titleOfInvention nucleic acid array
abstract The invention relates to an array consisting of oligonucleotide or polynucleotide probes which are immobilized on a solid support. The array is characterized in that sequences of a selection or all of the selective monocyte-macrophage genes mentioned in Tables 1-6 are bound to the surface. The array enables the diagnosis of rheumatoid arthritis and other chronic inflammatory diseases, an accompanying analysis of treatment effectiveness and the monitoring of side effects in anti-tumor necrosis factor (TNF) therapy and thus the selection of the most effective therapy for the respective patient with rheumatoid arthritis. The present invention further relates to a nucleic acid array for the prognosis and for the development of new anti-TNF-directed pharmaceuticals or those pharmaceuticals which intervene in its control loop.
priorityDate 2002-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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