http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-10230224-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_75734e96fdacaa1d3b9a688597d10bb5 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-40 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-40 |
filingDate | 2002-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a42fcd55f29338e54e15976f4baa6fff http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_188930734a1c50eabcb620614640b75d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c173395682c107b852dc28e4308a39c5 |
publicationDate | 2004-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | DE-10230224-A1 |
titleOfInvention | A process for the production of S-adenosyl-L-methionine by fermentation of genetically modified microorganisms |
abstract | The invention relates to a process for the preparation of S-adenosyl-methionine (SAM) with the following steps: a) implementation of the enrichment process and the SAM fermentation process for the enrichment of SAM in the production master, b) if appropriate isolation by disruption of the cells and if necessary purification of the SAM enriched in the production strain, in which the production strain is a prokaryotic or eukaryotic organism that overexperimented at least one of the genes selected from the group MUP1, MUP3, SAM3, MET28, BAS1, PHO2, GCN4, SIP18, or in which at least one copy of at least one of the genes selected from the group MIG1, SPE2, BIO3, ABD1, ERG6, STE14, PEM1, CTM1, HSL7, COQ5, HMT1, NOP2, DIM1, PET56, ALD6 and SNQ1, is inactivated or has a combination of these overexpressions and gene inactivations , The invention further relates to a prokaryotic or eukaryotic organism which overexpresses at least one of the genes selected from the group MUP1, MUP3, SAM3, MET28, BAS1, PHO2, GCN4, SIP18 or in which at least one copy of at least one of the genes is selected from the group MIG1, SAM3, SPE2, BIO3, ABD1, ERG6, STE14, PEM1, CTM1, HSL7, COQ5, HMT1, NOP2, DIM1, PET56, ALD6 and SNQ1, is inactivated or has a combination of these overexpressions and gene inactivations. Another object of the invention is the use of the above ... |
priorityDate | 2002-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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