| abstract |
The present invention relates to new 19-nor-17alpha-pregna-1,3,5 (10) -triene-17beta-ols with a 21,16alpha-lactone ring with a long-chain substituent in the 11beta position of the general formula II DOLLAR F1 in which R · 11 · is a long-chain alkyl radical containing a nitrogen atom, which may be terminally substituted by a perfluoroalkyl group. The compounds are tissue-selective as pure antiestrogens and are suitable for the production of medicinal products due to these properties. |