abstract |
The use of sialized carbohydrates of the following general formula I with at least one carbohydrate unit of the following general formula II is described: DOLLAR F1 in which DOLLAR A Sia means a sialic acid or a sialic acid derivative in an alpha2-3 bond, DOLLAR A Gal means a galactose-monosaccharide unit , DOLLAR A HexNac means an N-acetylated galactosamine or glucosamine monosaccharide unit (GalNAc or GlcNAc), DOLLAR A Hex means a galactose or glucose monosaccharide unit (Gal or Glc), DOLLAR AC for HexNac or Hex stands or is not present, DOLLAR A n stands for 1 to 50, DOLLAR AV stands for OH, a carbohydrate residue or for a connection point to a carrier T, with the proviso that if V stands for OH, n stands for 1, and , if V stands for a carbohydrate residue or for a carrier T, n is the number of carbohydrate units of the gen my formula II means DOLLAR F2 X for a sialic acid or a sialic acid derivative thereof, it being possible for a second sialic acid or a sialic acid derivative or more or more sialic acid or sialic acid derivatives in alpha2-8 bond to be bound to the sialic acid or the sialic acid derivative, a phosphate, sulfate or carboxyl group or a monosaccharide with a phosphate, sulfate or carboxyl group and only one of the radicals X is present, DOLLAR A for immunomodulation, for immunosuppression and for the prevention and treatment of infections in humans ... |