http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-102018214919-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8a5511d171c3e1eb82c61cf7e5ad1663 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4702 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D249-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D249-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 |
| filingDate | 2018-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c648f88b4f1d0548b8caa8147792cd3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f5547c08e0afa81e1b931e3a4ef3d27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8fef86b695d1e06e8b38f96c33fecc0a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_837fb5ca49dc32f040ec67ac15d38242 |
| publicationDate | 2020-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DE-102018214919-A1 |
| titleOfInvention | Acetyl-lysine mimicry and its production and use |
| abstract | The compound of the general formula I which can be prepared starting from 2-amino-heptanedioic acid is described their preparation and their racemates, tautomers, solvates and salts. In the formula, R 1 represents hydrogen, R 2 represents hydrogen or an amine protecting group or a linker molecule or an amino acid, R 3 represents a hydroxyl group or a protected hydroxyl group or a linker molecule or an amino acid. The compound can be incorporated as an amino acid building block in synthetic peptides. The compound itself and peptides comprising the compound as an amino acid building block are suitable for the production of medicaments, in particular for the therapy or prophylaxis of a disease which is based on a protein-protein interaction between a BET protein and a histone protein with at least one acetylated one Lysine goes back. Peptides with the compound can act as a BET inhibitor. |
| priorityDate | 2018-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 69.