http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-102017215159-B4
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a2bcaf91101a370a3d64e3190366357f |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5067 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5014 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-68 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 |
filingDate | 2017-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b899eec98625b7dadc5065d978a5864 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_332bacd3b20534958afe800b71bf2787 |
publicationDate | 2019-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | DE-102017215159-B4 |
titleOfInvention | Method for the determination of liver toxicity |
abstract | A method of determining hepatotoxicity, the method comprising the steps of: a) treating a liver cell line with TNF-a and a substance suspected of eliciting liver toxicity, b) determining the expression of at least one marker gene selected from the group consisting of: CXCL1, CXCL2, CSF3, BIRC3 and TXN, in the liver cell line treated with TNF-a and the substance, c) determining the viability of the liver cell line treated with TNF-a and the substance, d) determining liver toxicity based on the Expression of the at least one marker gene from step b) and the viability from step c) in comparison to a reference. |
priorityDate | 2017-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 358.