| abstract |
The invention is in the field of in vitro diagnostics and relates to an arrangement and method for enrichment and detection of cells in a liquid sample. For this purpose, the liquid sample is passed into a detection unit 10. In the sample, z. B. a blood sample are different cells, eg. B. to be detected tumor cells 31, 31 ', lymphocytes 33 and erythrocytes 35 which flow along the flow direction 15 through the detection unit 10 and flow. By means of a flow-limiting device 19, tumor cells 31, 31 'to be detected are retained or slowed down so that the tumor cells 31' can sink in the region of a microbalance 17 and be bound by antibodies on the surface of the microbalance. The lymphocytes 33 and erythrocytes 35, on the other hand, can pass unhindered through the flow restriction device due to their smaller size and / or greater deformability. |