http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-102009041893-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf920ea3ab8a199aef9a8dd334b2713b |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J1-0059 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J41-0094 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J1-0081 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J41-00 |
filingDate | 2009-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1523e71b88dc4ce0e3b863663d1045b9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_57e675aec5161508c7d6e3c1d10e0305 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c07ea04a44f2eb706a536026fea7ed32 |
publicationDate | 2010-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | DE-102009041893-A1 |
titleOfInvention | Process for the synthesis of diiron residue starting from estrone-3-methyl ether |
abstract | The invention relates to a process for the preparation of dieno-estrone from estrone methyl ether, comprising the steps of reacting estrone methyl ether in an alcohol in the presence of an acid with a trialkoxymethane to give 3-methoxy-17, 17-dialkoxy-estra-1,3,5-triene, Partial reduction of the reaction product by reaction with alkali metal in liquid ammonia to give 3-methoxy-17,17-dialkoxy-estra-2,5 (10) -diene, reaction of the weak acid reaction product to give 3-methoxy-estra-2,5 (10 ) -dien-17-one, reaction of the reaction product with cyanomethyl-lithium to give 3-methoxy-17α-cyanomethyl-17β-hydroxy-estra-2,5 (10) -diene, followed by reacting the reaction product with weak acid to give 17α-cyanomethyl -17β-hydroxy-estra-5 (10) -ene-3-one and reaction with pyridinium-bromine complex in pyridine to give dienogest. |
priorityDate | 2009-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 80.