http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-102009023162-B4
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_abb2737617f1075154acbf1754498ff5 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-75 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-75 |
filingDate | 2009-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2011-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_361986a85e30b42d27f30680090d3e1f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03a053d9d91ba8d1f60db15e3c26aa9d |
publicationDate | 2011-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | DE-102009023162-B4 |
titleOfInvention | Process for the preparation of flupirtine |
abstract | The present invention relates to a process for the preparation of flupirtine acid salt with the steps a) Hydrogenation of 2-amino-6- (4-fluorobenzylamino) -3-nitropyridine with palladium on charcoal in an inert, water-miscible solvent b) reaction of the obtained in a) 2,3-diamino-6- (4-fluorobenzylamino) pyridine to flupirtine by addition of ethyl chloroformate and a base c) filtration d) adding the filtrate from step c) with a solution of an acid or an acid salt in water e) precipitation of the flupirtine acid salt and filtration. |
priorityDate | 2009-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 49.