| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fab5a78161702097f97524ce6e5cdcd7 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0024
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-185 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3847
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3821
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0643 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-08 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0786 |
| filingDate |
2008-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d342e40997bebb0a75b6e0121450a906
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e43968c6c13a96ace5d9ac814f72a90 |
| publicationDate |
2010-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
DE-102008036060-A1 |
| titleOfInvention |
Cell-based method and means for bone formation |
| abstract |
The invention relates to the use of in vitro isolated or in vitro differentiated osteoclasts for bone augmentation, in particular by the in vivo application for inducing bone formation by attracting osteoblasts and preferably also vascular cells to a site of bone defect. The inventors have found that osteoclasts can regulate bone formation by secreting chemotactic factors and luring osteoblasts and vascular cells to the site of a bone defect. The invention further relates to the use of osteoclasts for the manufacture of a pharmaceutical composition or a medical product for bone augmentation or treatment of bone defects. |
| priorityDate |
2008-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |