| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_baf6a9f565fb456aa981d91a167106d4 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-20034
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-20022
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10343
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-23
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-585
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55516 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-33 |
| filingDate |
2008-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab90f0504bcc859039d3e6a3494c7281 |
| publicationDate |
2009-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
DE-102008010954-A1 |
| titleOfInvention |
DNA vaccine for the therapy and prophylaxis of cervical cancer and its premalignant precursors |
| abstract |
The present invention relates to a nucleic acid encoding one or more human papilloma virus (HPV) oncoproteins or fragments thereof. The nucleic acid, upon expression in a mammalian organism, can induce an immune response that results in the destruction of HPV oncoprotein expressing cells and thus is useful for the prophylaxis and / or treatment of HPV-induced diseases such as cervical cancer and its precursors. Compared to known nucleic acid vaccines, the construct according to the invention is distinguished by a safety concept which combines high therapeutic immunogenicity with maximum biological safety and thus creates the prerequisite for a broad and safe clinical application. |
| priorityDate |
2008-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |