| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_10bd7baf82e51a4b37e0e24ee06d11ef |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2503-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-025
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0629 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071 |
| filingDate |
2007-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5a372e78d3b07d53ec17542600153d2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ef439206d1d577a384a2e19651b10715
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3933efb09a80dcc858ce3aa318b40f8e |
| publicationDate |
2009-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
DE-102007035659-A1 |
| titleOfInvention |
Immortalized keratinocyte cell line and method of measuring protective agents |
| abstract |
The present invention relates to an immortalized keratinocyte cell line from the gingiva and a cell culture system in which the cell line is used to increase the effect of protective and / or modifying substances (eg anti-infective agents, oral care products) on the epithelial function of the gingiva / peridontium in vitro testing. The cells are infected with germs of the oral cavity and the effect of potentially protective and / or modifying substances on the cells is measured, for example by altering the transepithelial resistance (TEER). The invention thus replaces animal experiments and allows analysis in high through put. |
| priorityDate |
2007-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |