http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-102007018034-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cd0e6559b23f6e8c3dc91096d512942b |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06T2207-30024 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06T7-0012 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06V20-695 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06T7-90 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06T7-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06K9-00 |
filingDate | 2007-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a99484b31e0ef09eba906e0fea2f6e40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5b00055218d4c2d3662017288f0bff3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b3ca4876f4f3b5863005bfa0bb7d0b3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_504ba67c0e26c4b408bee43d41c5b34a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d49f59de2bc3557c226b8f7fcff560fc |
publicationDate | 2008-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | DE-102007018034-A1 |
titleOfInvention | Automatic image analysis and quantification for fluorescence in situ hybridization |
abstract | One known automated system for counting fluorescence signals obtained by FISH technology counts fluorescence signals based on two-dimensional images obtained by compressing three-dimensional information. Most of the three-dimensional information is lost. The new system automatically analyzes and counts fluorescence signals present in tissue, such as biopsy tissue, which has been labeled using, for example, FISH technique. Classes of a class network and processing steps of a processing hierarchy are specified. Thereafter, pixel values are captured three-dimensionally in sectional images of a tissue. A mesh structure is created by associating the pixel values with objects of a data network based on the class network and the processing hierarchy. Objects that have pixel values associated with them at different depths of tissue are used to determine the number of cell components, the volume of cell components, and the distance between cell components. In one application, fluorescence signals are counted to label Her-2 / neu genes and seventeen-chromosome centromeres to diagnose breast cancer. Overlapping or centromeric-covered Her-2 / neu genes can be accurately counted. No gene labeling signal artifacts can be identified by their volume. |
priorityDate | 2006-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.