http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-102006039646-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f0ac7efe04ec1931799a9d4a6429aa16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_34b94fc1e30b465788edca4767156299 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6a80ad4535ad6992c2f7c5f56e70a233 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-165 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0691 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071 |
| filingDate | 2006-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0bc24c7e495be560517bae58d0a781f2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9cef0235e16c0cae77028a512393764f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f77809d0ef9749ed7d64e3a3a8debc95 |
| publicationDate | 2008-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DE-102006039646-A1 |
| titleOfInvention | Method for the in-vitro production of three-dimensional tubule-shaped blood vessel endothelia |
| abstract | AnMethod for the in-vitro production of three-dimensional tubule-shaped blood vessel endothelianfrom single layer adherentngrowing endothelial cells was invented. Become endothelial cellsnsuspended in optimized medium and in culture bottles to the appropriatenCell density cultivated in the laboratory culture cabinet. Then bensuitable growth factors are added and the culture bottles arenCompletely filled air-free with optimized medium. The single-layered adherently growingnEndothelial cells are now either exposed to real weightlessnessnor on a machine such as the Random Positioning Machinenand thus kept under simulated weightlessness. If the effectnthe earth's gravity is abolished, the endothelial cells dissolvenwithin 24 to 48 hours from the surface of their culture vessel andnrearrangieren to three-dimensional tubule-shaped cell aggregates, whichnthe inner layer or intima of blood vessels, but at the same timenwith a lot of extracellularnMatrix are equipped. Such aggregates can be used as a model for studiesnof blood vessel endotheliumnassociated phenomena ornas starting material fornserve the production of transplantable blood vessel clauses. |
| priorityDate | 2006-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 47.