abstract |
ThenThe present invention relates to the use of certain spiro,nKetone and carboxylic acid compoundsnfor inhibiting the peptidyl prolyl cis / trans isomerase activity of cyclophilinsnand the use of these compounds for the preparation of a cosmeticnor pharmaceutical composition for promoting hair growth ornfor the treatment or prevention of autoimmune inflammatory diseases,nfungal diseases, bacterial infections,nof viral infections caused by parasites, Prozozoa or wormsnDiseases, of cancer, of diseases of cells, of fibrosingnDiseases, non-neoplastic changes and diseases,nthe on prions and changesnin the structure and function of cellular proteins and cells. |