http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-102006032427-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a9bbaf223591c3a53c384720211e0753 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-10 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5513 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0095 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-554 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-18 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-551 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-554 |
filingDate | 2006-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_949c513352f4ef09fb821f1edb3173f9 |
publicationDate | 2008-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | DE-102006032427-A1 |
titleOfInvention | Use of compositions of clozapine, quetiapine, hard or very poorly soluble acid addition salts of quetiapine and / or olanzapine for the preparation of solutions for oral administration |
abstract | The invention relates to the use of compositions with a) 10 to 200 mg / ml clozapine, 25 to 300 mg / ml quetiapine, 25 to 300 mg / ml (expressed as quetiapine base) of one or more difficultly or very slightly soluble acid addition salts of quetiapine and / or 1 to 20 mg / ml olanzapine as active substance (s), b) 0 to 20 mg / ml benzyl alcohol and / or phenylethyl alcohol, c) o to 200 mg / ml of propylene glycol, (d) from 0 to 50 mg / ml of one or more essential oils, flavorings and / or sweeteners and e) balance of 1 ml each of one or more liquid polyethylene glycol (s), poly [oxypropylene (s)], poloxamer (s), vegetable oil (s), medium chain triglycerides, polyoxyethylated (s) and polyoxypropylated fatty acid glycerides (s), low-viscosity / low-viscosity paraffin (s) and / or glycerol, wherein instead of c) or in addition to c) up to 50 mg / ml of ethanol and / or up to 0.5 wt .-%, based on the / the active ingredient (s), of one or more C 3-4 alkanol (s), for the preparation of solutions for oral administration, characterized in that the content of e) of peroxides <100 ppm and the content of the solution of residual oxygen <1 mg / ml. By the invention well drippable stable solutions are obtained. |
priorityDate | 2006-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 70.