| abstract |
The invention relates to the use of substituted piperazine and morpholine derivatives of the general formula I and / or II or their physiologically acceptable salts or a preparation containing at least one compound of the formulas I and / or II, in which R 1 to R 4 -H, -OH, -OA, -A, -OCOA R 1 and R 2 taken together may be -methylenedioxy or -ethylenedioxy, X is -O, -CH-R 4 , -NR 4 R 5 is -H, -A, -COOH, -COOA, -COA, -CONH 2 , -CONH 2 A A is alkyl or substituted alkyl radial, phenyl or substituted phenyl radical for the prophylaxis, improvement of the general skin condition and / or treatment of skin diseases, especially hyperpigmentation, as well as new piperazine derivatives. |