http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-102004043629-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cba14b4a47c59442a16f39859ad4c9d8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-32 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-31 |
| filingDate | 2004-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_269fc0aa27295de2ac7bf655dd996479 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b72a13b53c803d35978a928309ab72b1 |
| publicationDate | 2006-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DE-102004043629-A1 |
| titleOfInvention | Communication-mediating domains in nonribosomal peptide synthetases and their use for the generation of novel peptide antibiotics |
| abstract | objectnThe present invention relates to communication switching (COM) domains andntheir use fornthe generation of artificial biosynthetic complexes for productionnof peptides and depsi peptides, as well as peptide-based natural products andnDerivatives of natural products. COM domainsnare in naturalnBiosynthetic Complexes of Nonribosomal Peptide Synthetases (NRPSs)nand hybrid NRPS / polyketide synthases (PKSs) for the establishment of productivenInteractions between partner enzymes, as well as the simultaneous suppressionnnon-productive interactions between non-partner enzymesnresponsible. The knowledge of COM domains is used to pass throughnthe targeted use of compatible and non-compatible COM domain pairsna specific communication between natural non-partner enzymesnto force or an interaction between natural partner enzymesnprevention. According to the inventionnCOM domainsntherefore used as a universal tool to artificial biosynthetic complexesnfor anynPeptides, peptics and natural product derivatives with knownnor completelynnovel primary structuresnbuild. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107849542-A |
| priorityDate | 2004-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1019.