http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-102004027816-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bf6bf2b73446c82ae3f3cf592469fa7a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-505 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-505 |
| filingDate | 2004-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2006-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DE-102004027816-A1 |
| titleOfInvention | Process for the purification of erythropoietin |
| abstract | The present invention relates to a process for the production of recombinant erythropoietin which has a particularly high degree of purity (> = 98%). The process comprises at least 5 chromatographic purification steps, namely at least two anion exchange chromatographies, at least one hydrophobic interaction chromatography, at least one affinity chromatography and at least one hydroxyapatite chromatography. In preferred embodiments, the method omits any size exclusion chromatography and any reversed-phase chromatography. In particular, the invention relates to a process comprising the following chromatographic purification steps in the order given: i) a first anion exchange chromatography, ii) an affinity chromatography, which is preferably a dye affinity chromatography, iii) a hydrophobic interaction chromatography, iv) a Hydroxyapatite chromatography; and v) a second anion exchange chromatography. |
| priorityDate | 2004-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 67.