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filingDate 2001-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_19e159fcc577e6cf1d3bce2b91088849
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publicationDate 2002-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber DE-10158302-A1
titleOfInvention Coating of implantable metal bodies with bioactive materials
abstract Bioactive hydroxylapatite coatings with micro-surface structures have so far not been able to be implemented, or have been inadequate. So far, this has required complex and expensive process technologies. DOLLAR A The coating on electrically conductive metals is based on a crystallization of calcium phosphate by applying an electric field in an aqueous calcium phosphate solution. The cathode in the solution itself acts as a substrate and is thus coated during the electrochemical process. Similar to electrophoretic deposition, the positively charged ions migrate to the cathode and the negatively charged ions to the anode, whereby the coating is based on a local supersaturation of the solution. The process for producing bioactive layers on metallically conductive, implantable components is divided into two procedural steps. In the first step, the coating takes place with a calcium phosphate of the phases monetite and / or brushite; in the second procedural step, the conversion to the bioactive apatite structure takes place. DOLLAR A implants, which primarily have supporting functions, show an improved interaction in the biological system with this method. Roughened surfaces in particular are characterized by better growth of the cells. The aim of the invention is to thin porous or foam-like implant surfaces with hydroxyapatite using this method.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011049915-A3
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http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021116143-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108588792-A
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