| abstract |
The present invention relates to the 17-chloro-D-homo steroids of general formula I DOLLAR F1 wherein DOLLAR AR¶1¶ is a hydrogen atom or a C¶1-6¶-alkanoyl or benzoyl radical, DOLLAR AR¶2¶ a C¶1 6¶-alkyl group, DOLLAR AR¶3¶ is a hydrogen atom, a C¶1-6¶-alkyl, C¶1-6¶-alkanoyl or Benzoylylrest and DOLLAR AR¶4¶ a hydrogen atom, a C¶1-6 ¶-alkyl group, a C¶n¶F¶2n + 1¶ group in which N = 1, 2 or 3, or a C IDENTICAL CR¶5¶ group in which R¶5¶ a hydrogen atom, a C¶1-6¶-alkyl radical or an unsubstituted or substituted phenyl radical is DOLLAR A mean. DOLLAR A The new compounds are useful for male and female contraception without affecting other estrogen-sensitive organs such as the uterus or the liver. DOLLAR A They are also useful in the treatment of benign or malignant proliferative diseases of the ovary, such as ovarian carcinomas and granulosa cell tumors. |