| abstract |
A transdermal therapeutic system comprising a backing layer, a protective layer, and at least one drug-containing polymer matrix, wherein the drug is a steroid hormone or a combination of steroid hormones, and wherein the polymer matrix is a pressure-sensitive polyacrylate substantially free of functional groups as the base polymer which is a homopolymer, copolymer or block copolymer and is obtainable by polymerization of a monomer mixture, wherein the monomer mixture used to prepare the polyacrylate a. a monomer or a mixture of monomers from the group of esters of acrylic and / or methacrylic acid, which carry linear, branched or cyclic aliphatic C 1 -C 12 substituents without other functional groups is, and b. Acrylic acid, methacrylic acid, 2-hydroxyethyl acrylate, 2-hydroxyethyl methacrylate, 3-hydroxypropyl acrylate and / or 3-hydroxypropyl methacrylate in a total amount below 2 wt .-%. |